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myši inbredné CFTR

  1. Record numberd018181
    Date06.06.2025
    TypeM - MESH
    Topical termmyši inbredné CFTR
    Other termSlovak (Pseudonym) myši inbrídované CFTR
    Slovak (Pseudonym) myši inbredné, s inaktivovaným génom cystic fibrosis transmembrane conductance regulator
    Slovak (Pseudonym) myši inbrídované, s inaktivovaným génom cystic fibrosis transmembrane conductance regulator
    See also(Later heading) fibróza cystická
    UDCB01.050.050.199.520.520.445B01.050.150.900.649.313.992.635.505.500.400.445
    NoteA strain of mice widely studied as a model for cystic fibrosis. These mice are generated from embryonic stem cells in which the CFTR (cystic fibrosis transmembrane conductance regulator) gene is inactivated by gene targeting. As a result, all mice have one copy of this altered gene in all their tissues. Mice homozygous for the disrupted gene exhibit many features common to young cystic fibrosis patients, including failure to thrive, meconium ileus, and alteration of mucous and serous glands.
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Number of the records: 1  

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