Number of the records: 1
butionínsulfoximín
Record number d019328 Date 06.06.2025 Type M - MESH Topical term butionínsulfoximín See also (Skutočné meno) antimetabolity
(Skutočné meno) antimetabolity protinádorové
(Skutočné meno) inhibítory enzýmov
(Skutočné meno) látky rádioprotektívne
(Skutočné meno) rádiosenzibilizátory
UDC D02.886.030.676.620.125D12.125.166.676.620.125 Note A synthetic amino acid that depletes glutathione by irreversibly inhibiting gamma-glutamylcysteine synthetase. Inhibition of this enzyme is a critical step in glutathione biosynthesis. It has been shown to inhibit the proliferative response in human T-lymphocytes and inhibit macrophage activation. (J Biol Chem 1995;270(33):1945-7) 
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Number of the records: 1