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detoxikácia metabolická, fáza I

  1. Record numberd050216
    Date06.06.2025
    TypeM - MESH
    Topical termdetoxikácia metabolická, fáza I
    Other termSlovak (Pseudonym) detoxikácia metabolická oxidatívna
    Slovak (Pseudonym) detoxikácia, fáza I
    Slovak (Pseudonym) fáza I metabolickej detoxikácie
    See also(Skutočné meno) interakcie liekové
    UDCG03.171.450.500G03.787.225.450.500G07.690.725.225.450.500
    NoteFunctionalization of exogenous substances to prepare them for conjugation in PHASE II DETOXIFICATION. Phase I enzymes include CYTOCHROME P450 enzymes and some OXIDOREDUCTASES. Excess induction of phase I over phase II detoxification leads to higher levels of FREE RADICALS that can induce CANCER and other cell damage. Induction or antagonism of phase I detoxication is the basis of a number of DRUG INTERACTIONS.
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