Number of the records: 1
proteín komplexu tuberóznej sklerózy 1
SYS d000077004 LBL 00000nx^^^2200181-^^45^^ 005 20240119195324.4 100 $a 20190101asloy0103 ba0 152 $b mesh 250 $a proteín komplexu tuberóznej sklerózy 1 $x AD $x AE $x AG $x AI $x AN $x BI $x BL $x CF $x CH $x CL $x CS $x DE $x DF $x EC $x GE $x HI $x IM $x IP $x ME $x PD $x PH $x PK $x PO $x RE $x SD $x ST $x TO $x TU $x UL $x UR $8 slo 300 1-
$a 2019 (1997) $8 eng 330 1-
$a An intracellular signaling and tumor suppressor protein that forms a complex with TUBEROUS SCLEROSIS COMPLEX 2 PROTEIN (TSC2) and other signaling factors to negatively regulate MTORC1 signaling and affect cell growth and proliferation. Structurally, it interacts with TSC2 through its N-terminal, which also contains GSK-3BETA phosphorylation sites and a RHO-KINASE activation domain. It also contains a C-terminal coiled-coil domain and ezrin-radixin-moesin (ERM) domain. Mutations in the TSC1 gene are associated with TUBEROUS SCLEROSIS. $8 eng 450 $a hamartín $5 e $8 slo 686 $a D12.644.360.925 686 $a D12.776.476.932 686 $a D12.776.624.776.766 750 $a Tuberous Sclerosis Complex 1 Protein $8 eng 801 -0
$a SK $b BA006 $c 20190310 801 -2
$a SK $b BA006 $c 20190717 980 $x M
Number of the records: 1