Number of the records: 1
rozmanitosť protilátok
SYS d000916 LBL 00000cx--j22000003--45-- 005 20240119201241.9 100 $a 19920223csloy0103----ba0 152 $b mesh 250 $a rozmanitosť protilátok $x DE $x GE $x IM $x PH $x RE $8 slo 300 1-
$a 80 $8 eng 300 1-
$a Antibodies (1966-1969) $8 eng 300 1-
$a Antibody Specificity (1970-1979) $8 eng 330 1-
$a The phenomenon of immense variability characteristic of ANTIBODIES. It enables the IMMUNE SYSTEM to react specifically against the essentially unlimited kinds of ANTIGENS it encounters. Antibody diversity is accounted for by three main theories: (1) the Germ Line Theory, which holds that each antibody-producing cell has genes coding for all possible antibody specificities, but expresses only the one stimulated by antigen; (2) the Somatic Mutation Theory, which holds that antibody-producing cells contain only a few genes, which produce antibody diversity by mutation; and (3) the Gene Rearrangement Theory, which holds that antibody diversity is generated by the rearrangement of IMMUNOGLOBULIN VARIABLE REGION gene segments during the differentiation of the ANTIBODY-PRODUCING CELLS. $8 eng 450 $a Germ Line Theory $5 e $8 eng 450 $a teória zárodočnej línie $5 e $8 slo 450 $a rôznorodosť protilátková $5 e $8 slo 450 $a rôznorodosť protilátok $5 e $8 slo 450 $a diverzita protilátok $5 e $8 slo 450 $a diverzita protilátková $5 e $8 slo 550 $3 sllk_un_auth*d015321 $Y Gene Rearrangement $5 B $a zmena génového usporiadania 686 $a G05.365.036 686 $a G12.500.199 750 $a Antibody Diversity $8 eng 801 -0
$a US $b DNLM $c 19920223 801 -2
$a SK $b BA006 $c 20030303 801 -2
$a SK $b BA006 $c 20091130 980 $x M
Number of the records: 1