Number of the records: 1
pikrotoxín
SYS d010852 LBL 00000cx--j2200000---45-- 005 20240119201130.5 100 $a 19990101asloy0103----ba0 152 $b mesh 250 $a pikrotoxín $x AA $x AD $x AE $x AG $x AI $x AN $x BL $x CF $x CH $x CL $x CS $x EC $x HI $x IM $x IP $x ME $x PD $x PK $x PO $x RE $x SD $x ST $x TO $x TU $x UR $8 slo 300 1-
$a 1966 $8 eng 330 1-
$a A mixture of PICROTOXININ and PICROTIN that is a noncompetitive antagonist at GABA-A receptors acting as a convulsant. Picrotoxin blocks the GAMMA-AMINOBUTYRIC ACID-activated chloride ionophore. Although it is most often used as a research tool, it has been used as a CNS stimulant and an antidote in poisoning by CNS depressants, especially the barbiturates. $8 eng 450 $a 3,6-Methano-8H-1,5,7-trioxacyclopenta(ij)cycloprop(a)azulene-4,8(3H)-dione, hexahydro-2a-hydroxy-9-(1-hydroxy-1-methylethyl)-8b-methyl-, (1aR-(1aalpha,2abeta,3beta,6beta,6abeta,8aS*,8bbeta,9S*))-, compd. with (1aR-(1aalpha,2abeta,3beta,6beta,6abeta,8 $5 e $8 eng 450 $a Cocculin $5 e $8 eng 450 $a 3,6-metán-8H-1,5,7-trioxacyklopenta(ij)cykloprop(a)azulén-4,8(3H)-dión, hexahydro-2a-hydroxy-9-(1-hydroxy-1-metyletyl)-8b-metyl-, (1aR-(1aalfa,2abeta,3beta,6beta,6abeta,8aS*,8bbeta,9S*))-, zlúč. s (1aR-(1aalfa,2abeta,3beta,6beta,6abeta,8 $5 e $8 slo 450 $a kokulín $5 e $8 slo 550 $3 sllk_un_auth*d000931 $Y Antidotes $5 P $a antidotá 550 $3 sllk_un_auth*d000697 $Y Central Nervous System Stimulants $5 P $a stimulanciá centrálneho nervového systému 550 $3 sllk_un_auth*d003292 $Y Convulsants $5 P $a konvulzíva 686 $a D02.455.426.392.368.367.800 686 $a D02.455.849.765.636 686 $a D02.540.552 686 $a D20.215.784.500.647 686 $a D23.946.649 686 $a D26.667.750 750 $a Picrotoxin $8 eng 801 -0
$a US $b DNLM $c 19990101 801 -2
$a SK $b BA006 $c 20070706 801 -2
$a SK $b BA006 $c 20230607 980 $x M
Number of the records: 1