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osteokalcín

  1. Subject h.osteokalcín
    Subject h.Osteocalcin
    English X referencesBone Gla Protein
    Calcium-Binding Protein, Vitamin K-Dependent
    Gla Protein, Bone
    Vitamin K-Dependent Bone Protein
    Scope note in EnglishVitamin K-dependent calcium-binding protein synthesized by OSTEOBLASTS and found primarily in BONES. Serum osteocalcin measurements provide a noninvasive specific marker of bone metabolism. The protein contains three residues of the amino acid gamma-carboxyglutamic acid (Gla), which, in the presence of CALCIUM, promotes binding to HYDROXYAPATITE and subsequent accumulation in BONE MATRIX.
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