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sirtuíny

  1. Subject h.sirtuíny
    Subject h.Sirtuins
    Entry termsSIRT
    SIRTs
    proteíny podobné Sir2 proteínom
    Sir2-podobné proteíny
    sirtuín
    English X referencesSIRT
    Sir2-like Proteins
    Sirtuin
    Scope note in EnglishA homologous family of regulatory enzymes that are structurally related to the protein silent mating type information regulator 2 (Sir2) found in Saccharomyces cerevisiae. Sirtuins contain a central catalytic core region which binds NAD. Several of the sirtuins utilize NAD to deacetylate proteins such as HISTONES and are categorized as GROUP III HISTONE DEACETYLASES. Several other sirtuin members utilize NAD to transfer ADP-RIBOSE to proteins and are categorized as MONO ADP-RIBOSE TRANSFERASES, while a third group of sirtuins appears to have both deacetylase and ADP ribose transferase activities.
    See also reference (FX) in Slovak proteíny regulačné, pre tichú informáciu, Saccharomyces cerevisiae
    See also reference (FX) in English Silent Information Regulator Proteins, Saccharomyces cerevisiae
    Links (7) - ARTICLES
    (1) - MeSH descriptor
    (4) - CiBaMed
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