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spektrometria hmotnostná laserová matrixová, desorpčno-ionizačná

  1. Subject h.spektrometria hmotnostná laserová matrixová, desorpčno-ionizačná
    Subject h.Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
    Entry termsMALD-MS
    MALDI-MS
    MS-MALD
    SELDI-TOF-MS
    spektroskopia hmotnostná laserová desorpčno-ionizačná, s vylepšeným povrchom
    spektroskopia hmotnostná laserová matrixová, desorpčno-ionizačná
    spektrometria hmotnostná, s laserovou desorpciou/ionizáciou s pomocou matrice
    MALDI
    matricou asistovaná laserová desorpcia/ionizácia
    desorpcia/ionizácia laserom za spoluúčasti matrice
    spektrometria hmotnostná, s laserovou desorpciou/ionizáciou, povrchovo vylepšená
    English X referencesLaser Desorption-Ionization Mass Spectrometry, Matrix-Assisted
    MALD-MS
    MALDI
    Mass Spectrometry, Matrix-Assisted Laser Desorption-Ionization
    Mass Spectroscopy, Matrix-Assisted Laser Desorption-Ionization
    Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
    Spectroscopy, Mass, Matrix-Assisted Laser Desorption-Ionization
    Scope note in EnglishA mass spectrometric technique that is used for the analysis of large biomolecules. Analyte molecules are embedded in an excess matrix of small organic molecules that show a high resonant absorption at the laser wavelength used. The matrix absorbs the laser energy, thus inducing a soft disintegration of the sample-matrix mixture into free (gas phase) matrix and analyte molecules and molecular ions. In general, only molecular ions of the analyte molecules are produced, and almost no fragmentation occurs. This makes the method well suited for molecular weight determinations and mixture analysis.
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