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fosfatidylinozitol-3,4,5-trisfosfát 5-fosfatázy
Heslo fosfatidylinozitol-3,4,5-trisfosfát 5-fosfatázy Heslo anglicky Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases Odkazy fosfatidylinozitol-(3,4,5)-trisfosfát fosfatázy
SHIP fosfatázy
inozitol fosfatázy obsahujúce doménu homológnu s 2. doménou srcVysvetľujúca pozn. v angl. Phosphoinositide phosphatases that catalyze the dephosphorylation (hydrolysis) of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P(3)) to produce PtdIns(3,4)P(2), which negatively regulates the PI3K ( 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASES) pathways. They contain an SH2 DOMAIN and STERILE ALPHA MOTIF and have important functions in regulating the immune response and other cellular processes in vertebrates. 
predmetové heslo
Počet záznamov: 1