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steroid-17-alfa-hydroxyláza

Heslo	steroid-17-alfa-hydroxyláza
Heslo anglicky	Steroid 17-alpha-Hydroxylase
Odkazy	steroid-17-alfa-monooxygenáza steroid-17-hydroxyláza cytochróm P450 (17-alfa) steroid-17-monooxygenáza CYP17 P-450(c17) 17-alfa-hydroxyláza 17 alfa-hydroxyprogesterón aldoláza 17,20-lyáza 17,20-dezmoláza
Angl. X odkazy	17 alpha-Hydroxylase 17,20-Lyase CYP17 Cytochrome P-450(17 alpha) P450(c17) Steroid 17 alpha-Monooxygenase Steroid 17-Hydroxylase Steroid 17-Monooxygenase
Vysvetľujúca pozn. v angl.	A microsomal cytochrome P450 enzyme that catalyzes the 17-alpha-hydroxylation of progesterone or pregnenolone and subsequent cleavage of the residual two carbons at C17 in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP17 gene, generates precursors for glucocorticoid, androgen, and estrogen synthesis. Defects in CYP17 gene cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL) and abnormal sexual differentiation.
Pozri aj (FX) v slov.	hyperplázia adrenálna vrodená
Pozri aj (FX) v angl.	Adrenal Hyperplasia, Congenital
Odkazy	(3) - ČLÁNKY
	(1) - heslo MeSH
	(2) - CiBaMed

predmetové heslo

Počet záznamov: 1