A high-molecular-weight plasma protein, produced by endothelial cells and megakaryocytes, that is part of the factor VIII/von Willebrand factor complex. The von Willebrand factor has receptors for collagen, platelets, and ristocetin activity as well as the immunologically distinct antigenic determinants. It functions in adhesion of platelets to collagen and hemostatic plug formation. The prolonged bleeding time in VON WILLEBRAND DISEASES is due to the deficiency of this factor.
See also reference (FX) in Slovak
koagulanciá Weibelove-Paladeho telieska von Willebrandova choroba, typ 1 von Willebrandova choroba, typ 2 von Willebrandova choroba, typ 3 von Willebrandove choroby
predmetové heslo
Počet záznamov: 1
openseadragon
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