Substances that do not act as agonists or antagonists but do affect the GAMMA-AMINOBUTYRIC ACID receptor-ionophore complex. GABA-A receptors (RECEPTORS, GABA-A) appear to have at least three allosteric sites at which modulators act: a site at which BENZODIAZEPINES act by increasing the opening frequency of GAMMA-AMINOBUTYRIC ACID-activated chloride channels; a site at which BARBITURATES act to prolong the duration of channel opening; and a site at which some steroids may act. GENERAL ANESTHETICS probably act at least partly by potentiating GABAergic responses, but they are not included here.
Pozri aj (FX) v slov.
anestetiká celkové anxiolytiká hypnotiká a sedatíva
Pozri aj (FX) v angl.
Anesthetics, General Anti-Anxiety Agents Hypnotics and Sedatives
Odkazy
(1) - ČLÁNKY
(34) - heslo MeSH
predmetové heslo
openseadragon
Počet záznamov: 1
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