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amplifikácia génová
Č. záznamu d005784 Dátum 06.06.2025 Typ M - MESH Tematický termín amplifikácia génová Iný termín Slovenčina (Pseudonym) amplifikácia génov
Pozri tiež (Skutočné meno) dávka génová
MDT G05.308.250G05.365.590.310G05.558.315 Poznámka A selective increase in the number of copies of a gene coding for a specific protein without a proportional increase in other genes. It occurs naturally via the excision of a copy of the repeating sequence from the chromosome and its extrachromosomal replication in a plasmid, or via the production of an RNA transcript of the entire repeating sequence of ribosomal RNA followed by the reverse transcription of the molecule to produce an additional copy of the original DNA sequence. Laboratory techniques have been introduced for inducing disproportional replication by unequal crossing over, uptake of DNA from lysed cells, or generation of extrachromosomal sequences from rolling circle replication. predmetové heslo
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