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Lambertov-Eatonov myastenický syndróm
Č. záznamu d015624 Dátum 06.06.2025 Typ M - MESH Tematický termín Lambertov-Eatonov myastenický syndróm Iný termín Angličtina (Pseudonym) Eaton-Lambert Syndrome
Angličtina (Pseudonym) Myasthenic Syndrome, Lambert-Eaton
Slovenčina (Pseudonym) syndróm myastenický
Slovenčina (Pseudonym) Eatonov-Lambertov syndróm
MDT C04.588.614.550.500.225C04.730.856.490.225C10.114.656.150C10.574.781.588.225C10.668.758.725.150C20.111.258.500.150 Poznámka An autoimmune disease characterized by weakness and fatigability of proximal muscles, particularly of the pelvic girdle, lower extremities, trunk, and shoulder girdle. There is relative sparing of extraocular and bulbar muscles. CARCINOMA, SMALL CELL of the lung is a frequently associated condition, although other malignancies and autoimmune diseases may be associated. Muscular weakness results from impaired impulse transmission at the NEUROMUSCULAR JUNCTION. Presynaptic calcium channel dysfunction leads to a reduced amount of acetylcholine being released in response to stimulation of the nerve. (From Adams et al., Principles of Neurology, 6th ed, pp 1471) 
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