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myši SCID
Č. záznamu d016513 Dátum 06.06.2025 Typ M - MESH Tematický termín myši SCID Iný termín Angličtina (Pseudonym) SCID-hu Mice
Angličtina (Pseudonym) SCID Mice
Angličtina (Pseudonym) Severe Combined Immunodeficient Mice
Slovenčina (Pseudonym) myši, SCID mutanty
Slovenčina (Pseudonym) myši SCID-hu
Slovenčina (Pseudonym) myši s ťažkou kombinovanou imunodeficienciou
MDT B01.050.150.900.649.313.992.635.505.500.550.780 Poznámka Mice homozygous for the mutant autosomal recessive gene scid which is located on the centromeric end of chromosome 16. These mice lack mature, functional lymphocytes and are thus highly susceptible to lethal opportunistic infections if not chronically treated with antibiotics. The lack of B- and T-cell immunity resembles severe combined immunodeficiency (SCID) syndrome in human infants. SCID mice are useful as animal models since they are receptive to implantation of a human immune system producing SCID-human (SCID-hu) hematochimeric mice. 
predmetové heslo
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