Počet záznamov: 1

myši inbredné CFTR

Č. záznamu	d018181
Dátum	06.06.2025
Typ	M - MESH
Tematický termín	myši inbredné CFTR
Iný termín	Slovenčina (Pseudonym) myši inbrídované CFTR Slovenčina (Pseudonym) myši inbredné, s inaktivovaným génom cystic fibrosis transmembrane conductance regulator Slovenčina (Pseudonym) myši inbrídované, s inaktivovaným génom cystic fibrosis transmembrane conductance regulator
Pozri tiež	(Novšie záhlavie) fibróza cystická
MDT	B01.050.050.199.520.520.445B01.050.150.900.649.313.992.635.505.500.400.445
Poznámka	A strain of mice widely studied as a model for cystic fibrosis. These mice are generated from embryonic stem cells in which the CFTR (cystic fibrosis transmembrane conductance regulator) gene is inactivated by gene targeting. As a result, all mice have one copy of this altered gene in all their tissues. Mice homozygous for the disrupted gene exhibit many features common to young cystic fibrosis patients, including failure to thrive, meconium ileus, and alteration of mucous and serous glands.

predmetové heslo

Počet záznamov: 1