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receptory pre-B-buniek

Č. záznamu	d054420
Dátum	06.06.2025
Typ	M - MESH
Tematický termín	receptory pre-B-buniek
Iný termín	Slovenčina (Pseudonym) receptory pre-B buniek
MDT	D12.776.124.790.651.950.750D12.776.377.715.548.950.750D12.776.543.750.705.816.821.750
Poznámka	Membrane proteins in precursor B-LYMPHOCYTES (pre-B Cells). They are composed of membrane-bound MU IMMUNOGLOBULIN HEAVY CHAINS in complex with SURROGATE LIGHT CHAINS instead of conventional IMMUNOGLOBULIN LIGHT CHAINS. Only successful rearrangement of the VDJ segments, at the Ig heavy chain gene locus (IMMUNOGLOBULIN HEAVY CHAIN GENES), will generate mu heavy chains that can pair with surrogate light chains. Thus formation of the pre-B cell receptors is an important checkpoint in the development of mature B cells.

predmetové heslo

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