| Heslo | pikrotoxín
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| Heslo anglicky | Picrotoxin
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| Odkazy | 3,6-metán-8H-1,5,7-trioxacyklopenta(ij)cykloprop(a)azulén-4,8(3H)-dión, hexahydro-2a-hydroxy-9-(1-hydroxy-1-metyletyl)-8b-metyl-, (1aR-(1aalfa,2abeta,3beta,6beta,6abeta,8aS*,8bbeta,9S*))-, zlúč. s (1aR-(1aalfa,2abeta,3beta,6beta,6abeta,8
kokulín
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| Angl. X odkazy | 3,6-Methano-8H-1,5,7-trioxacyclopenta(ij)cycloprop(a)azulene-4,8(3H)-dione, hexahydro-2a-hydroxy-9-(1-hydroxy-1-methylethyl)-8b-methyl-, (1aR-(1aalpha,2abeta,3beta,6beta,6abeta,8aS*,8bbeta,9S*))-, compd. with (1aR-(1aalpha,2abeta,3beta,6beta,6abeta,8
Cocculin
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| Vysvetľujúca pozn. v angl. | A mixture of PICROTOXININ and PICROTIN that is a noncompetitive antagonist at GABA-A receptors acting as a convulsant. Picrotoxin blocks the GAMMA-AMINOBUTYRIC ACID-activated chloride ionophore. Although it is most often used as a research tool, it has been used as a CNS stimulant and an antidote in poisoning by CNS depressants, especially the barbiturates.
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| Farmakologický účinok | antidotá
stimulanciá centrálneho nervového systému
konvulzíva
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| Farmakologický účinok | Antidotes
Central Nervous System Stimulants
Convulsants
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