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serín/treonín kináza-2 bohatá na leucínové repetície
Heslo serín/treonín kináza-2 bohatá na leucínové repetície Heslo anglicky Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 Odkazy serín/treonín kináza-2 s repetíciami bohatými na leucín
dardarín proteín
LRRK2 proteín
PARK8 proteínVysvetľujúca pozn. v angl. A serine/threonine protein kinase with GTPase activity that contains 12 LEUCINE-rich repeats in its central region and 7 WD repeats C-terminal to its kinase and GTPase domains. It localizes to TRANSPORT VESICLES; the OUTER MITOCHONDRIAL MEMBRANE; and the GOLGI APPARATUS. It functions in PROTEIN TRANSPORT; regulates neuron morphology in the central nervous system, and also functions in the trafficking of SYNAPTIC VESICLES. Mutations in the LRRK2 gene have been identified in autosomal dominant cases of PARKINSON DISEASE (PARK8). 
predmetové heslo
Počet záznamov: 1