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serínproteáza HTRA2

Heslo	serínproteáza HTRA2
Heslo anglicky	High-Temperature Requirement A Serine Peptidase 2
Odkazy	serínpeptidáza HTRA2 peptidáza serínová HTRA2 HTRA2 proteáza HTRA serínpeptidáza 2 Omi serínproteáza
Vysvetľujúca pozn. v angl.	A serine peptidase that contains a C-terminal PDZ domain. It localizes to the mitochondrial membrane and intermembrane space, translocating to the cytoplasm following APOPTOSIS stimuli, such as UV irradiation; it promotes cell death by binding to and inhibiting INHIBITOR OF APOPTOSIS PROTEINS, resulting in an increase in activity of CASPASES. Mutations in the HTRA2 gene are associated with Type 13 PARKINSON DISEASE.
Pozri aj (FX) v slov.	PDZ domény
Pozri aj (FX) v angl.	PDZ Domains
Odkazy	(1) - heslo MeSH

predmetové heslo

Počet záznamov: 1