Počet záznamov: 1
pregnane receptor X, pregnánový
Heslo pregnane receptor X, pregnánový Heslo anglicky Pregnane X Receptor Odkazy pregnán X receptor
podrodina jadrových receptorov 1, skupina I, člen 2
SXR receptor
receptor pre steroidy a xenobiotiká
steroid X receptorVysvetľujúca pozn. v angl. Steroid receptor that binds and is activated by variety of endogenous compounds and XENOBIOTICS. It binds the response element in promoters of genes that encode CYTOCHROME P450 3A4 and ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B, MEMBER 1 proteins, and also activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs, and endogenous compounds. It is activated by the antibiotic RIFAMPICIN and various plant metabolites, such as hyperforin, guggulipid, colupulone, and ISOFLAVONES. 
predmetové heslo
Počet záznamov: 1