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degróny
Heslo degróny Heslo anglicky Degrons Odkazy C-degróny
D-box motif
D-box motív
box deštrukčný
motív deštrukčného boxu
boxy deštrukčné
N-degróny
PEST motív
PEST motif
PEST sekvenciaAngl. X odkazy C-Degrons
D-Box Motif
Destruction Box
Destruction Box Motif
Destruction Boxes
N-Degrons
PEST Motif
PEST SequenceVysvetľujúca pozn. v angl. Minimal elements within a protein that are sufficient for recognition and degradation by a proteolytic apparatus. Inherent degrons are comprised of short linear amino acid sequences and secondary protein structural features that increase the affinity to E3 LIGASE; and are involved in regulating the specificity and timing of PROTEIN DEGRADATION. Acquired degrons are mostly transient and conferred by post-translational modifications of specific amino acids within proteins. (From Mol Cell. 2016 Sep 15;63(6):1055-65) 
predmetové heslo
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