Počet záznamov: 1

properdín

Heslo	properdín
Heslo anglicky	Properdin
Odkazy	faktor komplementu P
Angl. X odkazy	Complement Factor P
Vysvetľujúca pozn. v angl.	A 53-kDa protein that is a positive regulator of the alternate pathway of complement activation (COMPLEMENT ACTIVATION PATHWAY, ALTERNATIVE). It stabilizes the ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb) and protects it from rapid inactivation, thus facilitating the cascade of COMPLEMENT ACTIVATION and the formation of MEMBRANE ATTACK COMPLEX. Individuals with mutation in the PFC gene exhibit properdin deficiency and have a high susceptibility to infections.
Farmakologický účinok	faktory imunologické
Farmakologický účinok	Immunologic Factors

predmetové heslo

Počet záznamov: 1