Počet záznamov: 1
zalcitabín
SYS d016047 LBL 00000cx--j22000003--45-- 005 20240119201252.1 100 $a 19920714csloy0103----ba0 152 $b mesh 250 $a zalcitabín $x AA $x AD $x AE $x AG $x AI $x AN $x BL $x CF $x CH $x CL $x CS $x EC $x HI $x IM $x IP $x ME $x PD $x PK $x PO $x RE $x SD $x ST $x TO $x TU $x UR $8 slo 300 1-
$a 94; was DIDEOXYCYTIDINE 1990-93 $8 eng 300 1-
$a Deoxycytidine/analogs & derivatives (1986-1989) $8 eng 300 1-
$a Dideoxynucleosides (1989) $8 eng 330 1-
$a A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication at low concentrations, acting as a chain-terminator of viral DNA by binding to reverse transcriptase. Its principal toxic side effect is axonal degeneration resulting in peripheral neuropathy. $8 eng 450 $a 2',3'-Dideoxycytidine $5 e $8 eng 450 $a Dideoxycytidine $5 e $8 eng 450 $a ddC (Antiviral) $5 e $8 eng 450 $a 2',3'-dideoxycytidín $5 e $8 slo 450 $a dideoxycytidín $5 e $8 slo 450 $a ddC (antivirotikum) $5 e $8 slo 550 $3 sllk_un_auth*d019380 $Y Anti-HIV Agents $5 P $a látky proti HIV 550 $3 sllk_un_auth*d000963 $Y Antimetabolites $5 P $a antimetabolity 550 $3 sllk_un_auth*d018894 $Y Reverse Transcriptase Inhibitors $5 P $a inhibítory reverznej transkriptázy 686 $a D03.383.742.680.245.500.950 686 $a D13.570.230.329.950 686 $a D13.570.230.500.925 686 $a D13.570.685.245.500.950 750 $a Zalcitabine $8 eng 801 -0
$a US $b DNLM $c 19920714 801 -2
$a SK $b BA006 $c 20011012 980 $x M
Počet záznamov: 1