Počet záznamov: 1
heterogenita genetická
SYS d018740 LBL 00000nx--j22000003--45-- 005 20240119200233.7 100 $a 19940419csloy0103----ba0 152 $b mesh 250 $a heterogenita genetická $x DE $x HI $x RE $8 slo 300 1-
$a 95 $8 eng 330 1-
$a The presence of apparently similar characters for which the genetic evidence indicates that different genes or different genetic mechanisms are involved in different pedigrees. In clinical settings genetic heterogeneity refers to the presence of a variety of genetic defects which cause the same disease, often due to mutations at different loci on the same gene, a finding common to many human diseases including ALZHEIMER DISEASE; CYSTIC FIBROSIS; LIPOPROTEIN LIPASE DEFICIENCY, FAMILIAL; and POLYCYSTIC KIDNEY DISEASES. (Rieger, et al., Glossary of Genetics: Classical and Molecular, 5th ed; Segen, Dictionary of Modern Medicine, 1992) $8 eng 686 $a G05.365.331 750 $a Genetic Heterogeneity $8 eng 801 -0
$a US $b DNLM $c 19940419 801 -2
$a SK $b BA006 $c 19990923 980 $x M
Počet záznamov: 1