Počet záznamov: 1
kináza fokálnej adhézie 1
Heslo kináza fokálnej adhézie 1 Heslo anglicky Focal Adhesion Kinase 1 Vysvetľujúca pozn. v angl. A non-receptor protein tyrosine kinase with PROTEIN PHOSPHATASE 1 regulatory activity that is localized to FOCAL ADHESIONS and is a central component of integrin-mediated SIGNAL TRANSDUCTION PATHWAYS. Focal adhesion kinase 1 interacts with PAXILLIN and undergoes PHOSPHORYLATION in response to adhesion of cell surface integrins to the EXTRACELLULAR MATRIX. Phosphorylated p125FAK protein binds to a variety of SH2 DOMAIN and SH3 DOMAIN containing proteins and helps regulate CELL ADHESION and CELL MIGRATION. 
predmetové heslo
Počet záznamov: 1