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proteín signálny, agouti
Heslo proteín signálny, agouti Heslo anglicky Agouti Signaling Protein Odkazy agouti signálny proteín Vysvetľujúca pozn. v angl. A secreted protein of approximately 131 amino acids (depending on species) that regulates the synthesis of eumelanin (brown/black) pigments in MELANOCYTES. Agouti protein antagonizes the signaling of MELANOCORTIN RECEPTORS and has wide distribution including ADIPOSE TISSUE; GONADS; and HEART. Its overexpression in agouti mice results in uniform yellow coat color, OBESITY, and metabolic defects similar to type II diabetes in humans. 
predmetové heslo
Počet záznamov: 1