Počet záznamov: 1
motív aktivačný imunoreceptorový, založený na tyrozíne
Heslo motív aktivačný imunoreceptorový, založený na tyrozíne Heslo anglicky Immunoreceptor Tyrosine-Based Activation Motif Vysvetľujúca pozn. v angl. A conserved AMINO ACID SEQUENCE located in the intracellular domains of a family of transmembrane proteins involved in various IMMUNE RESPONSES. The CONSENSUS SEQUENCE of this motif is YXXL(or I)X(6-8)YXXL(or I) (where X denotes any amino acid). When phosphorylated ITAM motifs provide docking sites for PROTEIN TYROSINE KINASES of the Syk family thus forming signaling complexes which lead to activation of immune responses. 
predmetové heslo
Počet záznamov: 1