Počet záznamov: 1
klozapín
SYS d003024 LBL 00000nz--a2200000o--4500 005 20250606214636.4 008 921119|||anznnbabn-----------|-a|a------ 040 $b slo $a DNLM $d BA006 065 $a D03.633.300.240.220 066 $a 01 $c 03 150 $a klozapín $x AA $x AD $x AE $x AG $x AI $x AN $x BL $x CF $x CH $x CL $x CS $x EC $x HI $x IM $x IP $x ME $x PD $x PK $x PO $x RE $x SD $x ST $x TO $x TU $x UR $2 slo 550 $7 sllk_us_auth*d012702 $Y Serotonin Antagonists $w P $a antagonisty serotonínu 550 $7 sllk_us_auth*d014150 $Y Antipsychotic Agents $w P $a antipsychotiká 550 $7 sllk_us_auth*d018756 $Y GABA Antagonists $w P $a antagonisty GABA 665 $a 91(75); was see under DIBENZAZEPINES 1975-90 $2 eng 665 $a Dibenzazepines (1971-1974) $2 eng 665 $a Piperazines (1971-1974) $2 eng 680 9-
$i A tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity. Agranulocytosis is a major adverse effect associated with administration of this agent. $2 eng 750 -2
$a Clozapine $2 eng 980 $x M
Počet záznamov: 1