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etopozid
SYS d005047 LBL 00000cz--a2200000o--4500 005 20250606213942.7 008 920725|||anznnbabn-----------|-a|a------ 040 $b slo $a DNLM $d BA006 065 $a D02.455.426.559.847.638.960.675.250 065 $a D04.615.638.960.675.250 065 $a D09.408.348.275 066 $a 01 $c 03 150 $a etopozid $x AA $x AD $x AE $x AG $x AI $x AN $x BL $x CF $x CH $x CL $x CS $x EC $x HI $x IM $x IP $x ME $x PD $x PK $x PO $x RE $x SD $x ST $x TO $x TU $x UR $2 slo 450 $w v $a Demethyl Epipodophyllotoxin Ethylidine Glucoside $2 eng 450 $w v $a Etoposide $2 slo 450 $w v $a demetylepipodofylotoxínetylidínglukozid $2 slo 550 $7 sllk_us_auth*d000972 $Y Antineoplastic Agents, Phytogenic $w P $a antineoplastiká fytogénne 550 $7 sllk_us_auth*d059005 $Y Topoisomerase II Inhibitors $w P $a inhibítory topoizomerázy II 665 $a 87(81); was see under PODOPHYLLOTOXIN 1981-86; was VP 16-213 see under PODOPHYLLOTOXIN 1976-80 $2 eng 665 $a Glucosides (1975) $2 eng 665 $a Glycosides (1973-1974) $2 eng 665 $a Podophyllotoxin (1973-1974)/analogs & derivatives (1975) $2 eng 680 9-
$i A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle. $2 eng 750 -2
$a Etoposide $2 eng 980 $x M
Počet záznamov: 1