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cilastatín

Č. záznamu	d015377
Dátum	06.06.2025
Typ	M - MESH
Tematický termín	cilastatín
Pozri tiež	(Skutočné meno) inhibítory proteáz
MDT	D02.455.426.392.368.533.200D10.251.355.325.200
Poznámka	A renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, IMIPENEM, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukotriene E4.

predmetové heslo

Počet záznamov: 1