Počet záznamov: 1
ubikvitín-proteín ligázy Nedd4
SYS d000075702 LBL 00000nx^^^2200181-^^45^^ 005 20240119195320.5 100 $a 20180101asloy0103 ba0 152 $b mesh 250 $a ubikvitín-proteín ligázy Nedd4 $x AD $x AE $x AI $x AN $x BI $x BL $x CF $x CH $x CL $x CS $x DE $x DF $x EC $x GE $x HI $x IM $x IP $x ME $x PD $x PH $x PK $x PO $x RE $x SD $x ST $x TO $x TU $x UL $x UR $8 slo 300 1-
$a 2018 (1996) $8 eng 330 1-
$a E3 ubiquitin ligases that consist of four WW DOMAINS. They accept UBIQUITIN from E2 UBIQUITIN-CONJUGATING ENZYME as a thioester via their C-terminal HECT domains and transfer it specifically to the 63rd LYSINE residue (Lys-63) of target proteins. NEDD4 targets include many proteins and receptors with important functions for cell growth and homeostasis such as VEGFR-2; FGFR1 TYROSINE KINASE; and ERBB-4 RECEPTOR. They play a critical role in the internalization of these receptors, their degradation by LYSOSOMES, and also function as part of the ESCRT complex in VIRUS RELEASE. $8 eng 450 $a Nedd4 proteíny $5 e $8 slo 450 $a ubikvitínligázy Nedd4 $5 e $8 slo 686 $a D05.500.199.500 686 $a D08.811.464.938.750.257 686 $a D12.776.543.990.493.500 750 $a Nedd4 Ubiquitin Protein Ligases $8 eng 801 -0
$a SK $b BA006 $c 20180615 801 -2
$a SK $b BA006 $c 20180808 801 -2
$a SK $b BA006 $c 20181105 980 $x M
Počet záznamov: 1