Počet záznamov: 1
cieľ rapamycínového komplexu 2, mechanistický
SYS d000076225 LBL 00000nx^^^2200181-^^45^^ 005 20240119195322.3 100 $a 20180101asloy0103 ba0 152 $b mesh 250 $a cieľ rapamycínového komplexu 2, mechanistický $x AD $x AE $x AG $x AI $x AN $x BI $x BL $x CF $x CH $x CL $x CS $x DE $x DF $x EC $x GE $x HI $x IM $x IP $x ME $x PD $x PH $x PK $x PO $x RE $x SD $x ST $x TO $x TU $x UL $x UR $8 slo 300 1-
$a 2018 (2013) $8 eng 330 1-
$a A multiprotein complex consisting of mTOR KINASE; MLST8 PROTEIN; rapamycin-insensitive companion of mTOR protein (RICTOR PROTEIN); and PRR5 (proline-rich protein 5). Like mTORC1, it also regulates cell growth and proliferation in response to growth factors but may not be as sensitive to nutrient availability and is insensitive to SIROLIMUS. In contrast to mTORC1, it can regulate the ACTIN CYTOSKELETON through RHO GTPASES to promote the formation of STRESS FIBERS. The mTORC2 complex also plays a critical role in AKT1 PROTEIN KINASE phosphorylation and activation. $8 eng 450 $a MTORC-2 $5 e $8 slo 450 $a TOR komplex 2 $5 e $8 slo 450 $a TORC2 $5 e $8 slo 450 $a cieľ rapamycínového komplexu 2 $5 e $8 slo 450 $a mTORC2 $5 e $8 slo 686 $a D05.500.356 686 $a D08.811.913.696.620.682.700.931.750 686 $a D12.776.476.563.931.750 750 $a Mechanistic Target of Rapamycin Complex 2 $8 eng 801 -0
$a SK $b BA006 $c 20180615 801 -2
$a SK $b BA006 $c 20180802 980 $x M
Počet záznamov: 1