Počet záznamov: 1
amilorid
SYS d000584 LBL 00000cx--j22000003--45-- 005 20240119200832.4 100 $a 19990101asloy0103----ba0 152 $b mesh 250 $a amilorid $x AA $x AD $x AE $x AG $x AI $x AN $x BL $x CF $x CH $x CL $x CS $x EC $x HI $x IM $x IP $x ME $x PD $x PK $x PO $x RE $x SD $x ST $x TO $x TU $x UR $8 slo 300 1-
$a 86(72); was see under PYRAZINES 1975-85, was Prov 1972-74 $8 eng 300 1-
$a Diuretics (1966-1971) $8 eng 300 1-
$a Pyrazines (1966-1971) $8 eng 330 1-
$a A pyrazine compound inhibiting SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with DIURETICS to spare POTASSIUM loss. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705) $8 eng 550 $3 sllk_un_auth*d062646 $Y Acid Sensing Ion Channel Blockers $5 P $a blokátory iónových kanálov citlivých na kyslosť 550 $3 sllk_un_auth*d004232 $Y Diuretics $5 P $a diuretiká 550 $3 sllk_un_auth*d062686 $Y Epithelial Sodium Channel Blockers $5 P $a blokátory epitelových sodíkových kanálov 686 $a D03.383.679.149 750 $a Amiloride $8 eng 801 -0
$a US $b DNLM $c 19990101 801 -2
$a SK $b BA006 $c 20070706 980 $x M
Počet záznamov: 1