Počet záznamov: 1
botulotoxíny
SYS d001905 LBL 00000cx--j2200000---45-- 005 20240119201326.4 100 $a 19990101asloy0103----ba0 152 $b mesh 250 $a botulotoxíny $x AD $x AE $x AG $x AI $x AN $x BI $x BL $x CF $x CH $x CL $x CS $x DE $x EC $x GE $x HI $x IM $x IP $x ME $x PD $x PH $x PK $x PO $x RE $x SD $x ST $x TO $x TU $x UL $x UR $8 slo 300 1-
$a 78; was BOTULINUM TOXIN 1969-77 (Prov 1969-71) $8 eng 300 1-
$a Clostridium Botulinum (1966-1968) $8 eng 300 1-
$a Toxins (1966-1968) $8 eng 330 1-
$a Toxic proteins produced from the species CLOSTRIDIUM BOTULINUM. The toxins are synthesized as a single peptide chain which is processed into a mature protein consisting of a heavy chain and light chain joined via a disulfide bond. The botulinum toxin light chain is a zinc-dependent protease which is released from the heavy chain upon ENDOCYTOSIS into PRESYNAPTIC NERVE ENDINGS. Once inside the cell the botulinum toxin light chain cleaves specific SNARE proteins which are essential for secretion of ACETYLCHOLINE by SYNAPTIC VESICLES. This inhibition of acetylcholine release results in muscular PARALYSIS. $8 eng 450 $a Botulin $5 e $8 eng 450 $a Botulinum Neurotoxin $5 e $8 eng 450 $a Botulinum Neurotoxins $5 e $8 eng 450 $a Clostridium botulinum Toxins $5 e $8 eng 450 $a botulín $5 e $8 slo 450 $a botulotoxíny klostrídiové $5 e $8 slo 450 $a neurotoxín Botulinum $5 e $8 slo 450 $a neurotoxíny botulínové $5 e $8 slo 450 $a toxíny Clostridium botulinum $5 e $8 slo 550 $3 sllk_un_auth*d065087 $Y Acetylcholine Release Inhibitors $5 P $a inhibítory uvoľňovania acetylcholínu 550 $3 sllk_un_auth*d009498 $Y Neurotoxins $5 P $a neurotoxíny 550 $3 sllk_un_auth*d001906 $Y Botulism $5 F $a botulizmus 550 $3 sllk_un_auth*d001906 $Y Botulism $5 B $a botulizmus 550 $3 sllk_un_auth*d003014 $Y Clostridium botulinum $5 B $a Clostridium botulinum 550 $3 sllk_un_auth*d018678 $Y Cholinergic Agents $5 B $a látky cholínergické 686 $a D08.811.277.656.300.480.153 686 $a D08.811.277.656.675.374.153 686 $a D12.776.097.156 686 $a D23.946.123.179 750 $a Botulinum Toxins $8 eng 801 -0
$a US $b DNLM $c 19990101 801 -2
$a SK $b BA006 $c 20070706 801 -2
$a SK $b BA006 $c 20210907 820 $a /antag permitted but consider also BOTULINUM ANTITOXIN $8 eng 980 $x M
Počet záznamov: 1