Počet záznamov: 1
etopozid
SYS d005047 LBL 00000cx--j22000003--45-- 005 20240119200949.9 100 $a 19920725csloy0103----ba0 152 $b mesh 250 $a etopozid $x AA $x AD $x AE $x AG $x AI $x AN $x BL $x CF $x CH $x CL $x CS $x EC $x HI $x IM $x IP $x ME $x PD $x PK $x PO $x RE $x SD $x ST $x TO $x TU $x UR $8 slo 300 1-
$a 87(81); was see under PODOPHYLLOTOXIN 1981-86; was VP 16-213 see under PODOPHYLLOTOXIN 1976-80 $8 eng 300 1-
$a Glucosides (1975) $8 eng 300 1-
$a Glycosides (1973-1974) $8 eng 300 1-
$a Podophyllotoxin (1973-1974)/analogs & derivatives (1975) $8 eng 330 1-
$a A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle. $8 eng 450 $a Demethyl Epipodophyllotoxin Ethylidine Glucoside $5 e $8 eng 450 $a Etoposide $5 e $8 slo 450 $a demetylepipodofylotoxínetylidínglukozid $5 e $8 slo 550 $3 sllk_un_auth*d000972 $Y Antineoplastic Agents, Phytogenic $5 P $a antineoplastiká fytogénne 550 $3 sllk_un_auth*d059005 $Y Topoisomerase II Inhibitors $5 P $a inhibítory topoizomerázy II 686 $a D02.455.426.559.847.638.960.675.250 686 $a D04.615.638.960.675.250 686 $a D09.408.348.275 750 $a Etoposide $8 eng 801 -0
$a US $b DNLM $c 19920725 801 -2
$a SK $b BA006 $c 20010625 980 $x M
Počet záznamov: 1