Počet záznamov: 1
lovastatín
SYS d008148 LBL 00000cx--j2200000---45-- 005 20240119201044.5 100 $a 19920504asloy0103----ba0 152 $b mesh 250 $a lovastatín $x AA $x AD $x AE $x AG $x AI $x AN $x BI $x BL $x CF $x CH $x CL $x CS $x EC $x GE $x HI $x IM $x IP $x ME $x PD $x PH $x PK $x PO $x RE $x SD $x ST $x TO $x TU $x UR $8 slo 300 1-
$a 88; for MONACOLIN K use LOVASTATIN (NM) 1980-98 $8 eng 300 1-
$a Anticholesteremic Agents (1966-1987) $8 eng 300 1-
$a Hydroxymethylglutaryl CoA Reductases/antagonists & inhibitors (1977-1987) $8 eng 300 1-
$a Naphthalenes (1966-1987) $8 eng 330 1-
$a A fungal metabolite isolated from cultures of Aspergillus terreus. The compound is a potent anticholesteremic agent. It inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It also stimulates the production of low-density lipoprotein receptors in the liver. $8 eng 450 $a Lovastatin, 1 alpha-Isomer $5 e $8 eng 450 $a Mevinolin $5 e $8 eng 450 $a lovastatín, 1 alfa-izomér $5 e $8 slo 450 $a mevinolín $5 e $8 slo 550 $3 sllk_un_auth*d000924 $Y Anticholesteremic Agents $5 P $a anticholesterolemiká 550 $3 sllk_un_auth*d019161 $Y Hydroxymethylglutaryl-CoA Reductase Inhibitors $5 P $a inhibítory hydroxymetylglutaryl-CoA-reduktázy 686 $a D02.455.426.559.847.638.400 686 $a D04.615.638.400 750 $a Lovastatin $8 eng 801 -0
$a US $b DNLM $c 19920504 801 -2
$a SK $b BA006 $c 20070706 801 -2
$a SK $b BA006 $c 20130201 980 $x M
Počet záznamov: 1