Počet záznamov: 1
tenipozid
SYS d013713 LBL 00000cx--j22000003--45-- 005 20240119201215.0 100 $a 19920725csloy0103----ba0 152 $b mesh 250 $a tenipozid $x AA $x AD $x AE $x AG $x AI $x AN $x BL $x CF $x CH $x CL $x CS $x EC $x HI $x IM $x IP $x ME $x PD $x PK $x PO $x RE $x SD $x ST $x TO $x TU $x UR $8 slo 300 1-
$a 91(81); was see under PODOPHYLLOTOXIN 1981-90; was VM 26 see under PODOPHYLLOTOXIN 1976-80 $8 eng 300 1-
$a Glucosides (1975) $8 eng 300 1-
$a Glycosides (1973-1974) $8 eng 300 1-
$a Podophyllotoxin (1973-1974) $8 eng 330 1-
$a A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent cells from entering into the mitotic phase of the cell cycle, and lead to cell death. Teniposide acts primarily in the G2 and S phases of the cycle. $8 eng 450 $a Demethyl Epipodophyllotoxin Thenylidine Glucoside $5 e $8 eng 450 $a demetylepipodofylotoxíntenylidínglukozid $5 e $8 slo 550 $3 sllk_un_auth*d000970 $Y Antineoplastic Agents $5 P $a antineoplastiká 550 $3 sllk_un_auth*d059005 $Y Topoisomerase II Inhibitors $5 P $a inhibítory topoizomerázy II 686 $a D09.408.348.800 750 $a Teniposide $8 eng 801 -0
$a US $b DNLM $c 19920725 801 -2
$a SK $b BA006 $c 20050424 980 $x M
Počet záznamov: 1