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proteín deglykáza DJ-1
Heslo proteín deglykáza DJ-1 Heslo anglicky Protein Deglycase DJ-1 Odkazy DJ-1 proteín
DJ1 proteín
DJ-1-PARK7 proteín
PARK7 proteín
proteín 7 spojený s Parkinsonovou chorobou
deglykáza asociovaná s parkinsonizmomVysvetľujúca pozn. v angl. A protein deglycase that repairs methylglyoxal- and glyoxal-glycated amino acids and proteins, releasing repaired proteins and lactate or glycolate. It deglycates CYSTEINE, ARGININE and LYSINE residues to reactivate proteins by reversing glycation and prevent the formation of ADVANCED GLYCATION END PRODUCTS. It protects cells against OXIDATIVE STRESS and CELL DEATH by functioning as an oxidative stress sensor and redox-sensitive MOLECULAR CHAPERONE and PROTEASE. Mutations in the PARK7 gene are associated with autosomal-recessive, early-onset PARKINSON DISEASE. 
predmetové heslo
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