Počet záznamov: 1

aflatoxín M1

Heslo	aflatoxín M1
Heslo anglicky	Aflatoxin M1
Odkazy	aflatoxín M(1) 4-hydroxyaflatoxín B1 aflatoxín M aflatoxín M1, cis(+-)-izomér
Angl. X odkazy	Aflatoxin M(1)
Vysvetľujúca pozn. v angl.	A 4-hydroxylated metabolite of AFLATOXIN B1, one of the MYCOTOXINS from ASPERGILLUS tainted food. It is associated with LIVER damage and cancer resulting from its P450 activation to the epoxide which alkylates DNA. Toxicity depends on the balance of liver enzymes that activate it (CYTOCHROME P-450) and others that detoxify it (GLUTATHIONE S TRANSFERASE) (Pharmac Ther 50.443 1991). Primates & rat are sensitive while mouse and hamster are tolerant (Canc Res 29.236 1969).
Farmakologický účinok	jedy
Farmakologický účinok	Poisons
Odkazy	(2) - ČLÁNKY

predmetové heslo

Počet záznamov: 1