Počet záznamov: 1
proteín MRE11, homológny
Heslo proteín MRE11, homológny Heslo anglicky MRE11 Homologue Protein Odkazy proteín MRE11A Vysvetľujúca pozn. v angl. A component of the MRN complex along with Rad50 and Nibrin. Together, these perform a critical function in the repair of DOUBLE-STRANDED DNA BREAKS; RECOMBINATIONAL DNA REPAIR; maintenance of TELOMERE integrity and MEIOSIS. MRE11, which contains a poly(ADP)-ribose binding motif and associates with PARP1, possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Mutations in the MRE11 gene are associated with ATAXIA-TELANGIECTASIA-like disorder 1. 
predmetové heslo
Počet záznamov: 1