The GENETIC RECOMBINATION of the parts of two or more GENES, including an ONCOGENE as at least one of the fusion partners. Such gene fusions are often detected in neoplastic cells and are transcribed into ONCOGENE FUSION PROTEINS.
An aberrant form of human CHROMOSOME 22 characterized by translocation of the distal end of chromosome 9 from 9q34, to the long arm of chromosome 22 at 22q11. It is present in the bone marrow cells of 80 to 90 per cent of patients with chronic myelocytic leukemia (LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE).
Pozri aj (FX) v slov.
proteíny fúzne, onkogénové
Pozri aj (FX) v angl.
Oncogene Proteins, Fusion
Odkazy
(21) - ČLÁNKY
(3) - heslo MeSH
(6) - CiBaMed
(4) - KNIHY
predmetové heslo
openseadragon
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