receptor enterotoxínový receptory pre guanylín-uroguanylín receptory GC-C guanylyl cykláza C receptor pre guanylyl cyklázu receptor pre guanylátcyklázu receptor enterotoxínový, tepelne stabilný
Vysvetľujúca pozn. v angl.
Guanylate cyclase-coupled receptors that bind bacterial ENTEROTOXINS, as well as the endogenous peptides guanylin and uroguanylin. Ligand binding stimulates production of CYCLIC GMP by EPITHELIAL CELLS of the intestinal lumen, altering barrier permeability and mucus secretion. Mutations in the gene (GUCY2C) encoding this receptor are associated with some cases of hereditary diarrhea (Diarrhea 6) and MECONIUM ILEUS.
