An alpha-globulin of about 453 amino acids, depending on the species. It is produced by the liver in response to lowered blood pressure and secreted into blood circulation. Angiotensinogen is the inactive precursor of the ANGIOTENSINS produced in the body by successive enzyme cleavages. Cleavage of angiotensinogen by RENIN yields the decapeptide ANGIOTENSIN I. Further cleavage of angiotensin I (by ANGIOTENSIN CONVERTING ENZYME) yields the potent vasoconstrictor octapeptide ANGIOTENSIN II; and then, via other enzymes, other angiotensins also involved in the hemodynamic-regulating RENIN-ANGIOTENSIN SYSTEM.
Farmakologický účinok
inhibítory serínových proteináz
Farmakologický účinok
Serine Proteinase Inhibitors
Odkazy
(11) - ČLÁNKY
(3) - CiBaMed
(2) - KNIHY
predmetové heslo
openseadragon
Počet záznamov: 1
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