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guanylátcykláza rozpustná

Subject h.	guanylátcykláza rozpustná
Subject h.	Soluble Guanylyl Cyclase
Entry terms	guanylátcykláza solubilná receptor pre kysličník dusnatý receptory pre oxid dusnatý guanylátcykláza citlivá na kysličník dusnatý
Scope note in English	A mammalian enzyme composed of a heterodimer of alpha and beta subunits. Each subunit consists of four domains; N-terminal HNOX domain, PAS-like domain, a coiled-coil domain, and a C-terminal catalytic domain. All four domains are homologous proteins with a similar conformation of functional domains. Soluble guanylate cyclase catalyzes the formation of cyclic GMP from GTP, and is a key enzyme of the nitric oxide signaling pathway involved in the regulation of a variety of biological and physiological processes in mammals.
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