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fosfatidylinozitol-3,4,5-trisfosfát 5-fosfatázy

Subject h.	fosfatidylinozitol-3,4,5-trisfosfát 5-fosfatázy
Subject h.	Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases
Entry terms	fosfatidylinozitol-(3,4,5)-trisfosfát fosfatázy SHIP fosfatázy inozitol fosfatázy obsahujúce doménu homológnu s 2. doménou src
Scope note in English	Phosphoinositide phosphatases that catalyze the dephosphorylation (hydrolysis) of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P(3)) to produce PtdIns(3,4)P(2), which negatively regulates the PI3K ( 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASES) pathways. They contain an SH2 DOMAIN and STERILE ALPHA MOTIF and have important functions in regulating the immune response and other cellular processes in vertebrates.

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Number of the records: 1