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lyzín acetyltransferáza 5
Subject h. lyzín acetyltransferáza 5 Subject h. Lysine Acetyltransferase 5 Entry terms HIV-1-Tat interaktívny proteín Tip60
HTATIP
KAT5 (TIP60) proteínScope note in English A catalytic subunit of the NuA4 histone acetyltransferase complex that functions in transcriptional activation of genes by acetylation of nucleosomal HISTONES H4 and H2A, altering nucleosome-DNA interactions and interaction of the modified histones with other activating transcription factors. It may control gene expression changes associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest; CELL AGING; APOPTOSIS; and DNA REPAIR. It is polyubiquitinated and degraded during HIV-1 infection through its interaction with the viral TAT PROTEIN. 
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