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faktor 1 viažuci pozitívnu regulačnú doménu I

  1. Subject h.faktor 1 viažuci pozitívnu regulačnú doménu I
    Subject h.Positive Regulatory Domain I-Binding Factor 1
    Entry termsBLIMP1 proteín
    PRDI-BF1 proteín
    PRDM1 proteín
    Scope note in EnglishA transcriptional repressor protein that contains an N-terminal PR-SET domain, four C-terminal CYS2-HIS2 ZINC FINGERS, and binds the PRDI element in the INTERFERON-BETA gene. It has methyltransferase activity and mediates gene transcription in tissue-specific innate and adaptive immune lymphocyte T-CELLS, repressing expression of proteins that promote exit of these tissue-specific T-cell populations from non-lymphoid organs.
    See also reference (FX) in Slovak PR-SET domény
    See also reference (FX) in English PR-SET Domains
    Links (1) - MeSH descriptor
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