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enzým deubikvitinačný CYLD
Subject h. enzým deubikvitinačný CYLD Subject h. Deubiquitinating Enzyme CYLD Entry terms enzým deubikvitinujúci CYLD
CYLD proteín
proteín asociovaný s cylindromatózou
proteín spojený s cylindromatózou
enzým deubikvitinačný, pri cylindromatózeScope note in English A deubiquitinase and tumor-suppressor protein that specifically cleaves LYSINE-63-linked polyubiquitin chains and also has endodeubiquitinase activity. It functions to regulate NF-KAPPA B and WNT SIGNALING PATHWAY activity, contributing to cell survival, proliferation, and differentiation. Mutations in the CYLD gene are associated with cases of FAMILIAL CYLINDROMATOSIS. 
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